The roles functions and researches of the p53 gene and how it can help in fighting cancer

If a person inherits only one functional copy of the p53 gene from their parents, they are predisposed to cancer and usually develop several independent tumors in a variety of tissues in early adulthood. This condition is rare, and is known as Li-Fraumeni syndrome. However, mutations in p53 are found in most tumor types, and so contribute to the complex network of molecular events leading to tumor formation. The p53 gene has been mapped to chromosome

The roles functions and researches of the p53 gene and how it can help in fighting cancer

Note that these values may differ depending on how and where the tree is grown. Resin Composition The resin component of Boswellia carterii is quite similar to the sacra species of frankincense: In a chemical point of view, Boswellia carteri and B. Boswellia carterii gum is a lot more palatable with a nice, slightly sweet, lemon-pine taste that leaves your mouth feeling refreshed.

Frankincense Types: Medicinal, Psychoactive, Cognitive, Scent Properties & More - The Revisionist

But there are a few problems when it comes to chewing the oleo-gum resin of Boswellia carterii. For instance, the gum content of carterii frankincense makes it so that sometimes when you try to chew it, it sometimes dissolves into a wet-gummy powder.

But most of the time, the Boswellia carterii can be chewed like a regular piece of chewing gum. Another problem is that I observe stomach problems when chewing Boswellia carterii tree gum. Specifically, carterii tears can act as a laxative. And sometimes there is minute amounts of stomach pain, which is a lot better compared to chewing papyrifera gum.

I would describe it as having a scent that is reminiscent a lemons, pine trees, turpentine, and very fresh. But if you burn the gum-resin for too long, and at too high of a temperature, you will start to notice a burnt wood smell after most of the essential oil has evaporated from the gum.

Which is usually caused by the gum burning at too high of a temperature. So far, scientists have discovered that the frankincense oil derived from the Boswellia carteri tree has an anti-cancerous effect, killing cancerous cells while leaving the healthy ones intact[18].

Indeed, the p53 network is as complex and enigmatic as it is relevant. It is the goal of this article, written 30 years after the discovery of p53, to present a concise review of the tumor suppressor role of the p53 network and to highlight the context-dependent nature of p53 target-gene functions. Medical Properties & Uses. Not all plants are good for the human being, but Boswellia carterii (and many other types of frankincense) may be a tree that scientist can look into for its medicinal properties. The p53 Gene and Cancer Development. One genetic protein that scientists are studying in detail for its role in cancer cell development is the p53 gene. Strengthening Your p53 Genes. The research is clear that the stability of your p53 genes is one of the most important factors in your risk for developing life-threatening cancers.

Although boswellic acid possesses anti-cancer properties, it is not found in the essential oil. So an essential oil will not have the full spectrum of therapeutic benefits as the whole oleo-gum resin would. But considering these facts, the study then indicates that the anti-cancer property comes from a chemical component of the essential oil.

By the way, the essential oil of Boswellia carterii seems to have an immunostimulatory property[20], meaning that it stimulates the production of lymphocytes a type of white blood cell.

And much of the information you can find online on carterii frankincense are user anecdotes. However, multiple user anecdotes that convey the same information start to show that piece of information as possibly true.

With that in mind, I went ahead and gathered the information that was held in common between multiple users: Many people have used Boswellia carterii essential oil as a topical pain reliever.

It seems people have experienced quite a bit of back pain relief when applying the Boswellia carterii frankincense essential oil to the painful spot. One person has also observed that the essential oil of Boswellia carterii stops migraines with sublingual application- specifically by placing a drop of the essential oil on the thumb and holding it against the roof of the mouth for a few seconds.

The user reported that after 5 minutes, their nausea and migraine dissipated and was no longer observable. Another user reports that the essential oil of Boswellia caterii greatly reduced the pain of Multiple Sclerosis and improved the duration of their sleep.

Of course, be forewarned that you should test whether you are sensitive to skin applications of essential oils by placing a single drop on your skin first to see if any redness develops. Of course, you should use essential topically with dilution.

Courtesy of African plants — A Photo Guide. Boswellia dalzielii is found to be quite toxic to mosquitoes as well. It was too soft, and easily melting in my mouth like butter.

But the taste is quite something else. Boswellia Dalzielli tastes like sweet lemons without the sharpness of citrus. The gum felt cool in my mouth, almost like peppermint.

The Expression of Genetics and Epigenetics

In fact, I would describe the taste to be reminiscence of peppermint. The Boswellia dalzielii tree is usually found in the savannas of Western Africa, growing up to about 13 meters in height.

It has small white fragrant flowers which bloom when the tree becomes leafless.

The roles functions and researches of the p53 gene and how it can help in fighting cancer

Description of the Bark: The tree is covered with pale papery-thin beige-colored bark that is naturally peeling and cracking off from the tree. Description of the Leaves: The leaves of the tree sprout out in clumps from specific parts of the tree, not even distributed.

The p53 tumor suppressor protein - Genes and Disease - NCBI Bookshelf

The leaves are pale yellow to light green in color. The leaves are very thin, narrow, long blades are are lined on the outer perimeter in a saw-tooth like fashion. Description of the Gum-resin: The gum resin tears that exude from the Boswellia dalzielii tree are whitish-yellow, sometimes with a greenish tint.Now, in world-first research, a team of researchers has uncovered a group of genes that is crucial to p53 effectively functioning in its cancer-preventing role.

Indeed, the p53 network is as complex and enigmatic as it is relevant. It is the goal of this article, written 30 years after the discovery of p53, to present a concise review of the tumor suppressor role of the p53 network and to highlight the context-dependent nature of p53 target-gene functions.

In case of irreparable damage, the p53 protein can help to trigger cell death. All cancer cells contain mutations in combinations of tumor suppressors and oncogenes. The removal of functional p53, the ‘guardian of the genome,’ from a cell allows for the accumulation of even more DNA damage and the division of cells that contain damaged DNA.

The p53 Gene and Cancer This Click and Learn explains the structure and function of the p53 protein as well as how the protein’s activity is regulated. HHMI BioInteractive. Medical Properties & Uses. Not all plants are good for the human being, but Boswellia carterii (and many other types of frankincense) may be a tree that scientist can look into for its medicinal properties.

A team from the Wellcome Trust Sanger Institute has found a major piece of biological evidence to support the role a group of virus-fighting genes has in cancer development.

What is Role of P53 Gene in Cancer? « CancerWORLD Cancer Treatment Research Journal